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In consideration of these public comments, and subsequent amendments made in section 221 of the CAEA, 2025 that amended the requirements we proposed to reflect in regulation per section 502 of the FCAOEA, 2024, we are finalizing the self-implementing conforming changes to the data reporting and phase-in of payment reductions at 42 CFR part 414, subpart G in accordance with section 221 of the CAEA, 2025

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This approach, which we've refined over years, allows us to consistently achieve the high purity levels essential for serious research