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410,411 Remarkably, patients with HER2+ advanced breast cancer achieved a significantly longer PFS using trastuzumab deruxtecan (T-DXd) than T-DM1 in the DESTINY-Breast03 trial

However, the assumption that TSPO PET accurately reflects activated microglia in humans is based on the observation of increased TSPO expression seen in mice 237

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Clinical symptoms were assessed using the Positive and Negative Syndrome Scale (PANSS)