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10.1016/j.nbd.2016.07.007 Neurobiol

Therefore, in the absence of significant active uptake transporter action, liver microsomes are more accurate (Bowman and Benet, 2019)

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In addition, preclinical trials showed that after an initial response of xenograft model of hepatocellular carcinoma to sorafenib (a multi-kinase inhibitor with antiangiogenic properties), the tumour progressed within a month due to the large-scale co-option of sinusoidal and portal tract vessels [54]