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A modification of the injury severity score that both improves accuracy and simplifies scoring

As approximately 98% of small-molecule drugs and most large-molecule neurotherapeutic agents are excluded from the brain by the BBB, efforts are underway to optimize effective delivery across the BBB for the achievement of therapeutic concentrations in brain tissue [84,85]

Yang J, Wang X, Sun Y, Chen B, Hu F, Guo C, et al

Genome-wide association studies (GWAS) and gene expression profiling have identified numerous genetic variants implicated in the initiation and progression of NAFLD