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The PUFAs have been observed to hinder the normal functioning of cells by creating cytotoxic protein adducts or by disrupting cell membranes through lipid peroxidation, leading to ferroptosis in IECs

Canonically, NETosis proceeds through a highly orchestrated series of intracellular events involving chromatin decondensation, histone citrullination mediated by peptidylarginine deiminase 4 (PAD4), and the translocation of neutrophil elastase (NE) and MPO from cytoplasmic granules into the nucleus, culminating in the extrusion of DNAprotein complexes into the extracellular space [45, 46]

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If the Elemental Diet resonates with you, it may be something for you to discuss with your doctor depending on your own symptoms, and how other interventions have worked for you

Chaudhary, D., Guleria, D., Aggarwal, H., Mishra, V., Chauhan, A., Dufoss, L., & Joshi, N