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Interestingly, the mRNA and protein expressions in intracellular transferrin receptor 1 (TFR1), ferritin heavy chain (FTH), or endogenous lipophilic antioxidant systems, such as solute carrier family 7 member 11 (SLC7A11), glutathione peroxidase 4 (GPX4), and FSP1, were not related to IMP-366s increased susceptibility to ferroptosis (Fig