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The reduction of BDNF levels negatively impacts the signaling pathways that facilitate LTP, as BDNF is known to enhance NMDA receptor activity and promote the incorporation of AMPA receptors into the postsynaptic membrane (Peregud et al

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Although small randomized trials and prospective registries report angiographic stabilization or regression and low event rates, adequately powered multicenter trials evaluating a whole-food plant-based diet as a standalone primary therapy for stable CAD are lacking