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Authors' contributions JC made substantial contributions to conception and design of the study, acquisition, analysis and interpretation of data, revised the manuscript critically for important intellectual content, and was a major contributor to writing the manuscript

This includes any possible side effects not listed in the package leaflet

Excessive activation of B and T lymphocytes leads to a significant increase in total hydrogen peroxide concentration, which will further lead to thyrocyte necrosis and apoptosis ( 4.2 Oxidative stress in PCOS Oxidative stress plays a very important role in the etiology of PCOS

Trimethylamine-N-Oxide (TMAO) predicts cardiovascular mortality in peripheral artery disease

PMCs express TLRs such as TLR1, 2 and 5 excluding TLR4, which play an important role in the membrane inflammation process (Colmont et al., 2011)