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Lets get anecdotes! He follows this up with, I think this could be big and, I did my research

Free radicals are highly reactive compounds created in the body during normal metabolic functions

However, if you have a low B12 level or a vitamin B12 deficiency, it can cause physical, neurological, and psychological problems

The toxicity models described earlier are also based on acute toxicity and a narcotic mode of action, although (as this chapter highlights) there are many other mechanisms of action and sublethal effects that have implications at the individual, population, and ecosystem levels as a result of both acute (not lethal and also including delayed responses) and chronic longer-term exposures

Duration of use: The drug is intended for prolonged use