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In-depth research into the pathological mechanisms of DKD should lead to the identification of new diagnostic markers and the development of therapeutic strategies

Key Points The hypoxia-inducible factor (HIF) oxygen-sensing pathway has a central role in regulating erythropoiesis

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Group 7 received local MSC and G-CSF via Hydrogel, an intravenous injection of MSC, and an injection into the gastrocnemius muscle with MSC and G-CSF dissolved in saline

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