glutathione-dependent formaldehyde oxidation pathway Overview of metabolism. (A) Summary The failure of two major

The failure of two major formaldehyde catabolism enzymes (ADH5 and ALDH2) leads to partial synthetic lethality in C57BL 6 mice Genes and Environment Springer Nature Link Endogenous formaldehyde scavenges cellular glutathione resulting in redox disruption and cytotoxicity Nature Communications Amino acid dependent formaldehyde metabolism in mammals Communications Chemistry Molecular Basis of Formaldehyde Detoxification: CHARACTERIZATION OF TWO S FORMYLGLUTATHIONE HYDROLASES FROM ESCHERICHIA COLI, FrmB AND YeiG ScienceDirect Unravelling Formaldehyde Metabolism in Bacteria: Road towards Synthetic Methylotrophy

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