S., Dhillon, D
Topical treatments may include creams and lotions that contain antioxidants and other ingredients that help to protect the skin from damage
131,132 In a clinical trial, a daily caffeine dose of 100 mg was shown to reduce "freezing." However, it appeared the subjects developed a tolerance after a few months

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It plays a key role in energy metabolism by transporting fatty acids into the mitochondria, where they are converted into energy