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Liraglutide attenuates glucolipotoxicity-induced RSC96 Schwann cells inflammation and dysfunction

This comprehensive mechanism distinguishes KLOW from single-peptide or three-component approaches

Nutrients 11(8):1926

We compared these scores to the Model for End-Stage Liver Disease (MELD), age, bilirubin, international normalized ratio, creatinine (ABIC), and Glasgow Alcoholic Hepatitis Score (GAHS) utilizing receiver operating characteristics (ROC) curves

Among the putative interactants related to signaling in KEGG pathways (Supplementary Data 4), we focused on TRAF2 because 1) TRAF2 modification with K63-linked chains serves as a hub for downstream NF-B signaling pathways 38 and 2) OTUD5 deubiquitylates the K63-ubiquitylated TRAF3, another TRAF-family protein 32