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HSPA12B attenuates cardiac dysfunction and remodeling after myocardial infarction through an eNOS-dependent mechanism

ME1, in contrast to ME2, lacks an allosteric site and does not have a dual cofactor specificity

Interestingly, this therapeutic effect does not rely on the functionality of transferred mitochondria but rather on their ability to trigger mitophagy, facilitating the removal of dysfunctional mitochondria and enhancing mitochondrial turnover

Subsequently, the cells were rinsed twice with pre-cooled PBS to remove residual medium and fixed with 4% paraformaldehyde (PFA) at room temperature for 30 min

Vitamin B7, also known as biotin, is a key component of many hair and nail supplements and is included in B complex