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At experimentally suitable concentrations (up to 100 M), we observed the appearance of Chc bound to three peptides and, although in much lower amounts, a fourth binding event was also detected (Supplementary Fig

Transient receptor potential (TRP) vanilloid 4 (TRPV4) is a member of the Ca 2+ -permeable TRP superfamily

Our protocol divides an infusion into multiple subcutaneous injections in order to administer it over time

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ASD Autism Spectrum Disorder DSM- V The fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM- V) defines ASD as having "deficits in social interaction and communication together with restricted and repetitive behaviors and interests" (American Psychiatric Association, 2013)