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Cell (2017) This landmark Cell publication from Erasmus University Medical Center introduced FOXO4-DRI as a senolytic peptide that selectively eliminates senescent cells by disrupting the FOXO4-p53 interaction

NAC is typically contraindicated in the case of gastritis or peptic ulcers, and in some people it can cause stomach irritation or sulfurous gas

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The microscopy images showed cell rupture and lysis (H&E stain), indicative of signs of cell death (TUNEL stain) in the tumor tissue (Fig