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Gunma Oncology Study Group (GOSG)

Hooker, S.W

10.1111/j.2042-7158.1995.tb05752.x 27 DouC.LiuZ.TuK.ZhangH.ChenC.YaqoobU.et al (2018)

It has been reported that elevated expressions of vascular endothelial growth factor (VEGF) and interleukin 8 (IL8) induce the production of vascular endothelial cells in ectopic endometrial lesions and that anti-VEGF/VEGF receptor treatments suppress the development of endometriosis in animal models [12, 13]

Trial data consistently show the combination arms exceeding cagrilintide-alone arms 15.6% vs 8.1% at 32 weeks in the Phase 2 diabetes trial (Frias et al., 2023), and a 22.7% combination figure at 68 weeks in REDEFINE 1 (Aronne et al., 2025)