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Under certain conditions, such as non-alcoholic steatohepatitis (NASH), the liver is subjected to significant oxidative stress

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Activation of the Nrf2ARE Pathway Curcumin also exerts its antioxidant effects through activation of the nuclear factor erythroid 22-related factor 2 (Nrf2) signaling pathway, a master regulator of cellular defense against oxidative stress [63,64]