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The metabolism and clearance of both components may be affected by significant liver disease, and patients with severe hepatic impairment should be monitored closely if treatment is deemed necessary

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Diagnosis may involve MRI and EMG

Prepare injections in a clean area, use aseptic technique, disinfect vial stoppers, and use a new sterile needle and syringe for every preparation and administration

Semaglutide is unique in its once-weekly dosing option for both diabetes management and weight loss, offering convenience and potentially improved adherence compared to other GLP-1 receptor agonists