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doi: 10.3389/fchem.2019.00043 162 HarwoodC

Future investigations based on the MAD theory should take care when taking approaches to target only single microbes such as HSV-1 or else using a broad-spectrum antibiotic without an anti-biofilm measure, as such strategies would likely be only partially productive

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The analyses of 4MSOB ITC and its conjugates were conducted using an Agilent HP1260 Series instrument coupled to an API5000 tandem mass spectrometer (AB Sciex, Darmstadt, Germany) by loading extracted samples onto an Agilent Zorbax Eclipse XDB-C18 column (50 4.6 mm 1.8 m, Agilent Technologies, Waldbronn, Germany) with mobile phase A (0.05% formic acid in milliQ water) and mobile phase B (acetonitrile)