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[DOI] [PMC free article] [PubMed] [Google Scholar] 58.Pott J., Kabat A

Mechanisms of CVD and CKD in patients with diabetes Vascular damages of ASCVD in patients with diabetes are characterized by endothelial and vascular smooth muscle cell dysfunction [12]

They demonstrated that human pancreatic tumor and stellate cells activate/process GSAO into its active metabolite and that GT activity positively correlates with GSAO-mediated proliferation arrest of co-cultured endothelial cells ( Figure 3B )

Some limitations of antibodies for clinical use are slow diffusion into tumor tissue, limited in vivo stability, and high production costs [7, 11, 12]