Excitingly the authors discovered that the initial PTT cleared the primary tumors whilst producing tumor-associated antigens which worked in combination with the immunotherapeutic to protect against recurrence and metastasis (Mei et al., 2019)
Anstee 51 , Stephen Harrison 52 , Patrick Bossuyt 2 and Michael Pavlides 53 , (1)University of Oxford, (2)University of Amsterdam, (3)The University of Jordan, (4)Institute of Digestive Disease, the Chinese University of Hong Kong, (5)Medical Data Analytics Centre (MDAC), the Chinese University of Hong Kong, (6)Versantis AG, (7)Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, (8)Medical University of Vienna, (9)Medical University of Graz, (10)Department of Medical Sciences, University of Torino, (11)University of Turin, (12)Octavian Fodor Regional Institute of Gastroenterology and Hepatology, 400162 Cluj-Napoca, Romania, (13)Department of Medicine, McGill University Health Centre, Westmount, QC, Canada, (14)University of Malaya, (15)University of Malaysia, Kuala Lumpur, Malaysia, (16)Wenzhou Medical University, (17)Storr Liver Centre, Westmead Hospital, Westmead Millennium Institute for Medical Research and University of Sydney, Westmead, New South Wales, Australia, (18)The University of Sydney, (19)Section of Gastroenterology and Hepatology, Dipartimento Di Promozione Della Salute, Materno Infantile, Medicina Interna e Specialistica Di Eccellenza (PROMISE), (20)Nottingham University Hospital NHS Trust and University of Nottingham, Nottingham, UK, (21)University of Nottingham, (22)Gachon University Gil Medical Center, (23)Department of Health, Medicine and Caring Sciences, Linkping University, Linkping, Sweden, (24)University Hospital of Montpellier, (25)University Hospital Bordeaux, (26)Department of Visceral Surgery and Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland, (27)Bern University Hospital, University of Bern, (28)Houston Research Institute, Houston, TX, (29)Cedars-Sinai Medical Center, Los Angeles, CA, (30)Service Hpato-Gastroentrologie Et Oncologie Digestive, Centre Hospitalier Universitaire, Angers, France
In conclusion, the future of glaucoma research should focus on integrating advanced diagnostic tools, personalized treatment strategies and innovative drug delivery systems, while addressing the challenges of accessibility, affordability and safety
, 45 , 1461-1480, doi: Teskey, G., Abrahem, R., Cao, R., Gyurjian, K., Islamoglu, H., Lucero, M., Martinez, A., Paredes, E., Salaiz, O., Robinson, B., and Venketaraman, V
Work in cell and animal models has examined NNMT inhibition alongside metabolic phenotyping, adipose tissue signaling, and broader NAD pathway readouts, although findings can vary by model design and assay conditions
