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Role of hypoxia in the tumor microenvironment and targeted therapy

The second kinase that activated our fasting reporter, KIN-2, is the ortholog of PKA, which has previously been shown to phosphorylate HNF4 during fasting 64

The modified GPx-DTNB method showed a linear range of 21000 U.L 1 of GPx activity, with a high degree of linearity (Pearson's r value of 0.999) and sensitivity (LOQ of 1 U.L 1 and LOD of 3 U.L 1 )

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