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Lebers disease (hereditary optic nerve atrophy) Polycythemia vera Low potassium levels (hypokalemia) History of blood clots Preparation Details Avoid alcohol when receiving B12 shots

Biphasic dose-response A pattern where a compound stimulates growth at low concentrations but inhibits it at higher concentrations

[329] [330] In February 2022, he said that he has "been about 80% plant-based for the past five years of my life", [331] and in 2025 he said that eats "mostly plants." [332] He also says that while he occasionally still consumes smaller amounts of animal products, following a mostly plant-based diet is better for his "overall-health", and that James Cameron helped him to understand that it is better for the environment

Individual results vary based on baseline metabolic health, lifestyle factors, and protocol adherence