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Baumann M, et al

43 , 1408 (2010) F.M

MDR1, also known as permeability glycoprotein ( P-gp ), is a transmembrane transport protein that recognizes and controls drug efflux from tumor tissues and eventually promotes drug resistance in breast cancer by altering drug distribution in tumors 52

TEM analysis revealed that the mitochondrial cristae structure was disordered in PTDSS1-knockdown cells, with numerous blank areas indicating mitophagy

While this gliotoxin oxidase activity cannot be ruled out completely, our demonstration that GliT exhibits gliotoxin reductase activity (Figure 5) suggests that direct gliotoxin reduction is a pre-requisite for secretion from A