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For example, in high-density co-cultures of astrocytes, BDNF secretion effectively rescues propofol-induced neuronal death, whereas low-density astrocytes, which secrete insufficient BDNF, fail to provide the same protection (Liu et al

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One study enrolled older adult inpatients with depression without an explicitly stated diagnostic framework

This concept is legitimate in the broader peptide literature, with some compounds demonstrating this kind of brain-targeted delivery via nasal administration