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Major clinical studies conducted to evaluate the effects of various dietary interventions and supplements on the symptoms of ASD are summarized in Table 1

However, compared with the intensive mechanistic studies of carnitine in mammals, the majority of the studies of carnitine in fish have only focused on the effects of carnitine on the fishs growth and body composition, whereas studies on the systemic regulation of nutritional metabolism by carnitine in fish, and the underlying mechanisms, are lacking

It forms acyl-carnitine esters with acyl-CoA derivatives, enabling entry into the mitochondrial matrix where -oxidation generates acetyl-CoA and ultimately ATP