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Although Ser can support one-carbon metabolism as a methyl donor, it is less likely that animals increase serinogenesis for methyl groups as the SAAR diet has other fungible methyl donors - choline and glycine (Supplementary Table 1a)

According to research on their subcellular location in hepatocytes, Cu,Zn-SOD (SOD1), which contains copper and zinc, can be found in the intermembrane space between the mitochondria as well as in the cytoplasm, peroxisomes, lysosomes, and nuclei [29]

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