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[10] have shown that muscle-specific loss of carnitine acetyltransferase (CrAT) in mice led to an accumulation of acetyl-coenzyme A (CoA) within the mitochondria and allosteric inhibition of pyruvate dehydrogenase (PDH), which subsequently impaired glucose utilization

Introduction One-third of the worlds Western population suffers from Non-Alcoholic Fatty Liver Disease (NAFLD) [1]