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These characteristics not only alter the nutritional quality of the food but may also contribute to an increased production of carcinogenic metabolites by disrupting the gut microbiota environment (41, 42)

Ultrastructural analysis via transmission electron microscopy revealed notable mitochondrial damage in neurons post-TBI, with both WT and FGF21 KO mice exhibiting significant alterations

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By contrast, coIP is not affected by any of the mutations of the S3 and S4 doublets (Fig

It has been demonstrated that oxidative stress and excessive generation of ROS affect mitochondrial morphology 30