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We visualized the regulated sites as a function of treatment by hierarchical clustering of the averaged phosphorylation site intensities per replica, which grouped likely substrates and targets according to the kinase inhibited (Fig

discoideum (mainly seen 24 h after infection) whose impact on host cell metabolism is summarized by the authors in two major conclusions: (a) enzymatic activities involved in bacterial degradation, protein biosynthesis, and fatty acid modification are down-regulated and (b) expression of genes involved in metabolic activities that ultimately generate products needed for the proliferation of the pathogen is induced

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We estimated meta-analyzed effect sizes and standard errors for each variant and calculated p-values based on a normal distribution

As of January 2025, 18 registered strategies involving MSC-based treatments for lumbar intervertebral disc degeneration have been documented (Table 4), providing important references for the development of cell therapies for disc degeneration