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The compound's structure(E)-4-hydroxy-N'-(naphthalen-2-ylmethylene)benzohydrazideallows it to interact favorably with key residues in the ERR ligand-binding pocket

This method allows self-administration of NAD at home (after medical guidance) and provides high bioavailability without the need for an IV line

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An accurate injection was associated with good pain reduction with VAS (visual analogue score) and Constant score returning to pre-injection level at six weeks in all patients