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Footnotes Edited by: Bernd Rosenkranz, Fundisa African Academy of Medicines Development, South Africa Reviewed by: Kacper Nijakowski, Poznan University of Medical Sciences, Poland Miriam Njoki Karinja, Science for Africa Foundation, Kenya Data availability statement The original contributions presented in the study are included in the article/Supplementary Material, further inquiries can be directed to the corresponding author

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**UPDATE** Safety rules changed in 2015, and many varnishes contain N -Methyl-2-pyrrolidone (NMP) as a solvent, in addition to water

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