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The role of GSH in metal-chelation lies behind its significance as a precursor for the synthesis of phytochelatins (PCs, family of peptides structurally related to GSH) in metal-exposed plants (Clemens, 2008)

Vitamin K compounds (phylloquinone, menaquinone-4/MK4, menadione) exhibit broad-spectrum ferroptosis suppression via a non-canonical FSP1-mediated pathway, identifying them as critical substrates for an endogenous anti-ferroptotic system independent of GSH/GPX4 (86)

A meta-analysis showed that silymarin significantly lowers aminotransferase levels and enhances insulin sensitivity in patients with NAFLD, offering a promising therapeutic option that aligns with dietary and lifestyle modifications typically recommended for managing liver conditions

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