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[Abstract] SW1990 cells expressing the indicated Flagc-Jun were pretreated with NCT-503 (40 M) and were cultured in glucose-free DMEM for 12 h

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On the other hand, clinical trials for benign prostatic hypertrophy indicate that when DHT levels are lowered by finasteride, a 5-reductase-2 inhibitor, normal men exhibit a drop in total sperm counts, sperm concentration and sperm volume, which appear reversible after discontinuation of the drug (45)