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10.3390/antiox12091739 [DOI] [PMC free article] [PubMed] [Google Scholar] Yang M., Chen Y., Huang X., Shen F., Meng Y

10.1016/j.cell.2015.10.001 116 ShawP.ChattopadhyayA

CRISPR interference (CRISPRi) screens using dCas9-KRAB enable efficient and uniform repression of target genes with limited cellular toxicity 39,40 , whereas primary cortical culture 41,42 captures physiological aspects of human cortical neurogenesis, supporting sensitive detection of cell fate choices