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A key enzyme in the anabolic utilization of ketone bodies is cytosolic acetoacetyl-CoA synthetase, which catalyses the coupling of acetoacetate to CoA in a reaction dependent on ATP with acetoacetyl-CoA as the product

The importance of passive data collecting, and wearable devices becomes even more evident when it comes to the correlation between fatigue and other factors influencing the QoL, like ADL, social functioning, but also other comorbidities like depression or sleep disorders

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Differential cerebral PA concentrations resulting from distinct administration routes likely underlie these varied outcomes

& Chenard, C.A