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This process causes calcium ions to enter cells via NMDA receptor channels, leading to neuronal damage and eventual cell death, and is called excitotoxicity

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coli using shake flasks, to avoid the need for a specialised fed-batch fermentation system and high-pressure equipment

Also, iridoid glycosides (at 50180 mg kg 1 day 1 p.o.) for 34 weeks can significantly promote NGF and BDNF production [48,49,50], and repair the abnormal functions of microglia, oligodendrocyte, and T cell to maintain the central nervous system homeostasis [48]

The same samples were then placed in an autoclave at 120 C for 20 min and a second reading of the EC (EC2) was made after cooling the solution to room temperature