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(5) facilitating passive targeting and drug accumulation in malignant tumors and other pathological sites via the enhanced permeability and retention (EPR) effect

The gene expression profiling results revealed that NAC treatment changed the expression of genes related to immune response, inflammatory response, oxidation-reduction processes, cytokine-cytokine receptor interactions, and cytokine-mediated signalling, Toll-like receptor signalling, Jak-STAT signalling, TNF signalling pathways

39 Previous reports have found that long-term liver iron overload leads to liver fibrosis, cirrhosis, and even the development of hepatocellular carcinoma (HCC)

The multivariate cross-products added 28 more that were higher in nonexercise than postexercise and 10 higher in postexercise

ROS can damage cellular components such as lipids, proteins, and DNA, leading to cell death and loss of cardiac contractile function