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GHK-Cu stimulates angiogenesis primarily through upregulation of key growth factors including vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF/FGF-2), with research demonstrating that GHK-Cu at nanomolar concentrations increases VEGF expression in dermal fibroblasts and stimulates human umbilical vein endothelial cell (HUVEC) proliferation through enhanced VEGF and FGF-2 expression

In the future, AOD 9604 is expected to become an important drug in the field of local fat reduction, providing a safer and more effective treatment option for obese patients

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PLoS ONE 16 , e0249594 (2021)