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The study utilized white non-thoroughbred male rats weighing 180-200g

Importantly, arterial stiffness was improved in WS patients as NR significantly improved the cardioankle vascular index (CAVI), a measure of arterial stiffness

Studied in patients with unresectable melanoma, it showed comparable CD4 + , CD8 + , and CTL responses to T cell therapy when used alone or with PD-1 checkpoint inhibitors (Sahin et al., 2020)