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et al., 2023) the cAMP/PKA/p-CREB pathway was altered in the amygdala alongside neuronal apoptosis (Jiang et al., 2023), and cortical cytokinesincluding IL-1, IL-6, and TNF- were elevated (Wang J

In the paracellular route, analytes traverse the inter-endothelial junctions (IEJs), which permit the passage of small molecules - generally molecules smaller than ~70 kDa - through diffusion and advection [44]

Nat Rev Neurol 14:606617

Studies show that growth hormone receptors are present in the brain, and GH plays roles in cognitive function, memory, and mood

[DOI] [PubMed] [Google Scholar] Foyer C.H., Bloom A.J., Queval G., Noctor G