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Neurological functions Several neurological diseases, such as Alzheimers disease and Parkinsons disease, are characterized by disrupted metabolism of the redox-active metals copper and/or iron and/or non-redox zinc (Simunkova et al

Heme is formed from succinyl CoA and glycine and is ultimately involved in aerobic metabolism after it is combined with globin chains that are synthesized on the ribosomes in the plasma of the developing erythrocyte

Cell lines Hucct1, RBE, and AML12 cell lines were purchased from Procell with short tandem repeat (STR) identification and cultured in RPMI 1640 (Hucct1 and RBE) with 10% fetal bovine serum or DMEM/F12 (AML12) with 10% fetal bovine serum, 1ITS-G, 40 ng/mL dexamethasone in incubator (37 C, 5% CO 2 )

At the mechanistic level, these interventions stimulate proprioceptive pathways, promote neuroplasticity, and regulate neurotransmitter balance, which collectively contribute to functional recovery 68 (Fig