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(134) confirmed that high concentrations of BCAAs promote oxidative stress, inflammation, and migration in human peripheral blood mononuclear cells through mTORC1 activation

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L-carnitine emerged as one of the few dietary supplements showing significant efficacy in reducing fatigue in ME/CFS patients according to a systematic review, notwithstanding methodological limitations such as small sample size and potential selection bias [136]

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This includes minimizing exposure to cigarette smoke, air pollution, pesticides, and harsh chemicals in household products and personal care items