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The differentially expressed genes were filtered using the condition Fold change 2 or 2 and the genes that fulfilled that condition were listed (Supplementary Data 13)

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Biphasic half-life [edit] Many drugs show a biphasic decline in plasma concentration after a dose: a steep distribution phase as drug leaves the central compartment for tissues ( phase), followed by a shallower elimination phase as drug is cleared ( phase)

Macrophages are derived from monocytes, which circulate through the blood for one to three days before migrating into tissues, where they become macrophages or dendritic cells