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Svedlund A, Hallbook T, Magnusson P, Dahlgren J, Swolin-Eide D

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Hypoxia increases hexosamine biosynthetic pathway gene transcription and O-glycosylated protein levels, and the O-linked N-acetylglucosaminylation of proteins is necessary for the survival of hypoxic pancreatic cancer cells[38]

In the study by Ricciolini and colleagues, labelled [U- 14 C]glucose was not incorporated into PUFAs, unlike [1- 14 C]-acetylcarnitine [109], indicating that the formation of acetyl groups from pyruvate in mitochondria ensures complete metabolism

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