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During sepsis, immune cells such as neutrophils and macrophages are rapidly activated in response to microbial invasion, releasing large amounts of ROS, including superoxide anion (O 2 ), hydrogen peroxide (H 2 O 2 ), and hydroxyl radicals (OH ), as part of the hosts antimicrobial arsenal (Di Meo et al., 2016)

Hagiwara, H

Animal experiments were approved by the Wako Animal Experiment Committee in RIKEN (approval number: W2021-2-020(1))

In colorectal tumor-bearing mice, the ketogenic formula suppressed systemic inflammation associated with tumors, such as lowering plasma IL-6 levels (150)