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Overexpression of COX2 is reported in many types of cancer, including cutaneous melanoma, which contributes to tumor progression and angiogenesis (225)

Fumarates promote cytoprotection of central nervous system cells against oxidative stress via the nuclear factor (erythroid-derived 2)-like 2 pathway

In plants, ROS are continuously produced under normal physiological conditions within membrane-bound organelles such as mitochondria, chloroplasts, and peroxisomes, as well as in other cellular compartments

Liver fibrosis mouse models were generated by high-fat, high-cholesterol diet or methionine- and choline-deficient diet

10.1007/s12035-023-03379-8 32 ChenY.GuoX.ZengY.MoX.HongS.HeH.et al (2023b)