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doi: 10.1016/j.molcel.2019.02.038 46 HuJTianM

10.3390/ijms14047405 78 ZhangB.ShangS.ZhangH.JabeenZ.ZhangG

The HMGB1/5HT7R/Nrf2/xCT/GPX4 pathway was found to promote ferroptosis of M2 microglia in transient middle cerebral artery occlusion (tMCAO) mice, which promoted ischemic brain injury and depressive-like behaviors

RT and PTT and DMXAA-mediated activation of the cGAS-STING pathway promote DCs maturation, increase the CD8 + T-cell ratio and the M1/M2 ratio, and decrease the T reg ratio (Fig