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In conclusion, TGR5/GPBAR1 is a pivotal receptor linking microbiota-derived SBAs to the modulation of inflammation and cell function within the TIME

Minimally invasive procedures, which can destroy enlarged prostate tissue or widen the urethra, include: Transurethral microwave thermotherapy High-intensity focused ultrasound Transurethral electrovaporization Water-induced thermotherapy Prostatic stent insertion Prostatic Urethral Lift (PUL), also known as UroLift Transurethral needle ablation (TUNA) (9) Surgery may be necessary if medication and minimally invasive procedures are ineffective

Paoletti A, Pencharz PB, Ball RO, Kong D, Xu L, Elango R, Courtney-Martin G. The Minimum Methionine Requirement for Adults Aged 60 Years Is the Same in Males and Females. Nutrients. 2023 Sep 23;15(19):4112. doi: 10.3390/nu15194112

The models were implemented at voxel-level in the Sandwich Estimator Toolbox [31] (version 2.1.0)

doi: 10.3389/fnut.2021.745609